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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
17.58
Human Site:
T321
Identified Species:
29.74
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
T321
P
L
L
E
G
P
Q
T
D
G
V
T
I
G
D
Chimpanzee
Pan troglodytes
XP_511585
968
108684
K325
A
P
V
D
S
M
L
K
D
M
A
T
I
I
L
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
T414
P
L
L
E
G
P
Q
T
D
G
V
T
I
G
D
Dog
Lupus familis
XP_853409
975
109686
T321
P
L
L
E
G
P
Q
T
D
G
V
T
I
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
T323
P
L
L
E
G
P
Q
T
D
G
V
T
I
G
D
Rat
Rattus norvegicus
XP_573211
965
109012
D318
T
D
G
V
T
I
G
D
K
G
E
C
V
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
G316
K
F
A
S
S
L
K
G
E
N
K
L
D
Y
W
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
T326
A
R
V
D
G
P
T
T
Q
D
V
T
L
K
E
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
E315
G
L
T
L
A
R
I
E
G
P
M
T
A
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
Y317
G
E
H
Q
K
G
L
Y
A
L
P
S
L
V
D
Honey Bee
Apis mellifera
XP_392044
968
110555
D316
Y
A
L
P
S
L
V
D
L
T
T
A
T
I
S
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
P329
Y
S
P
K
L
L
G
P
P
L
L
E
G
P
A
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
F341
P
L
L
E
G
P
G
F
D
G
I
T
P
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
K321
A
L
Q
N
T
F
S
K
D
G
M
C
I
A
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
20
100
100
N.A.
100
6.6
N.A.
0
N.A.
33.3
20
N.A.
6.6
6.6
0
60
P-Site Similarity:
100
33.3
100
100
N.A.
100
13.3
N.A.
13.3
N.A.
60
26.6
N.A.
26.6
6.6
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
8
0
8
0
0
0
8
0
8
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% C
% Asp:
0
8
0
15
0
0
0
15
50
8
0
0
8
0
36
% D
% Glu:
0
8
0
36
0
0
0
8
8
0
8
8
0
0
8
% E
% Phe:
0
8
0
0
0
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
15
0
8
0
43
8
22
8
8
50
0
0
8
36
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
0
0
8
0
43
22
0
% I
% Lys:
8
0
0
8
8
0
8
15
8
0
8
0
0
8
0
% K
% Leu:
0
50
43
8
8
22
15
0
8
15
8
8
15
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
8
15
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
36
8
8
8
0
43
0
8
8
8
8
0
8
15
8
% P
% Gln:
0
0
8
8
0
0
29
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
8
22
0
8
0
0
0
0
8
0
0
8
% S
% Thr:
8
0
8
0
15
0
8
36
0
8
8
58
8
0
8
% T
% Val:
0
0
15
8
0
0
8
0
0
0
36
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
15
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _